Prime Immunity

Description

Prime Immunity contains 250mg of beta-glucan, which has been the subject of more than 800 scientific studies and is recognized for its support of the immune system. Our purified beta glucans are derived from the yeast Saccharomyces cerevisiae, the most effective source. Among its many immune-boosting effects, it has been shown to stimulate neutrophil (a type of white blood cell) activity, improve antioxidant function, decrease tissue-damaging cytokine inflammation, and improve microbial balance. It is recommended to use regularly to improve resilience to infections, as well as during times of acute illness to accelerate recovery.

Prime Immunity Ingredients

Whole Glucan Particle (providing beta-glucan naturally derived from Saccharomyces cerevisiae), Dicalcium phosphate anhydrous, HPMC (capsule), stearic acid, magnesium stearate, silica, and medium-chain triglyceride oil.

Prime Immunity Directions

• For ongoing immune support: Take one capsule daily, first thing in the morning or last thing at night (before or well after a meal), with a full 8 oz glass of water. For fast-acting immune support:
• Take up to two capsules per day, as above; or use as directed by your healthcare practitioner.*
• Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner. Do not use if the tamper seal is damaged.

Prime Immunity Does NOT Contain

Wheat, gluten, corn, yeast protein, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

Sources:

1. Tian J, Ma J, Wang S, et al. Increased expression of mGITRL on D2SC/1 cells by particulate β-glucan impairs the suppressive effect of CD4(+)CD25(+) regulatory T cells and enhances the effector T cell proliferation. Cell Immunol. 2011 May 10;270(2):183-7. [PMID: 21636079]
2. Feldman S, Schwartz HI, Kalman DS, et al. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. J Appl Res. 2009 March-June;9(1&2):30-42. Accessed September 9, 2011.
3. Driscoll M, Hansen R, Ding C, et al. Therapeutic potential of various beta-glucan sources in conjunction with anti-tumor monoclonal antibody in cancer therapy. Cancer Biol Ther. 2009 Feb;8(3):218-25. [PMID: 19106638]
4. Liang, J., D. et al. Enhanced clearance of a multiple antibiotic-resistant Staphylococcus aureus in rats treated with PGG-glucan is associated with increased leukocyte counts and increased neutrophil oxidative burst activity. Int J Immunopharmacol. 1998 Nov;20(11):595-614. [PMID: 9848393]
5. Vetvicka V. Glucan-immunostimulant, adjuvant, potential drug. World J Clin Oncol. 2011 Feb 10;2(2):115-9. [PMID: 21603320]
6. Vetvicka V, Terayama K, Mandeville R, et al. Pilot study: orally-administered yeast ß1,3-glucan prophylactically protects against anthrax infection and cancer in mice. JANA. 2002;5(2):5-9. Reprint. Accessed August 21.
7. Natural Standard Database. Accessed July 23, 2011.
8. Yan J, Allendorf DJ, Brandley B. Yeast whole glucan particle (WGP) beta-glucan in conjunction with antitumour monoclonal antibodies to treat cancer. Expert Opin. Biol Ther. 2005 May;5(5):691-702. [PMID: 15934844]
9. Qi C, Cai Y, Gunn L, et al. Differential pathways regulating innate and adaptive antitumor immune responses by particulate and soluble yeast-derived ß-glucans. Blood. 2011 Jun 23;117(25):6825-36. [PMID: 21531981]
10. Pelizon AC, Kaneno R, Soares AM, et al. Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae. Physiol Res. 2005;54(5):557-64. [PMID: 16238470]
11. Tsikitis V, Albina J, Reichner J. Beta-glucan affects leukocyte navigation in a complex chemotactic ingredient. Surgery. 2004 Aug;136(2):384-9. [PMID: 15300205]
12. Senoglu N, Yuzbasioglu MF, Aral M, et al. Protective effects of N-acetylcysteine and beta-glucan pretreatment on oxidative stress in cecal ligation and puncture model of sepsis. J Invest Surg. 2008 Sep-Oct;21(5):237-43. [PMID: 19160131]
13. Turnbull, JL, Patchen ML, Scadden DT. The polysaccharide, PGGglucan, enhances human myelopoiesis by direct action independent of and additive to early-acting cytokines. Acta Haematol. 1999;102(2):66-71. [PMID: 10529508]
14. Kournikakis B, Mandeville R, Brousseau P, et al. Anthrax-protective effects of yeast beta 1,3 glucans Med Gen Med. 2003 Mar 21;5(1):1. [PMID:12827062]

Note: *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.